Next, install the aforementioned winetricks in your new prefix. It is important that you use these next commands any time you want to run or install ANYTHING inside of that 32-bit WINEPREFIX. Remember, we need at least .NET Framework 4.6 to run PKHeX and we must install .NET Framework 4.6 in the 32-bit prefix, therefore we will be running PKHeX from inside of the 32-bit prefix. (I know, don't ask, lol)